Inhibition of malate dehydrogenase via nanoselenium coupling with nanocellulose composite in MCF-7 breast carcinoma cells

Abstract Background Cancer, a leading cause of mortality worldwide, continues to pose significant challenges in treatment and management.Conventional therapies often face limitations, including lack of selectivity, adverse effects, and the development of resistance mechanisms.Methods Therefore, this study aims to investigate nanocellulose, nanosele

read more


Inferring Causal Direction From Multi-Dimensional Causal Networks for Assessing Harmful Factors in Security Analysis

In many scenarios of security analysis, Bayesian methods are often used for assessing harmful factors like attacks, as Bayesian causal model can estimate or predict the effect from the observed factors.To distinguish which ones are direct or significant causal (harmful) factors to the target systems, we often need to calculate a (local) causal netw

read more

CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis

Abstract Autophagy and apoptosis are involved in myocardial ischemia/reperfusion (I/R) injury.Research indicates that circular RNA HIPK3 (circHIPK3) is crucial to cell autophagy and apoptosis in various cancer types.However, the role of circHIPK3 in the regulation of cardiomyocyte autophagy and apoptosis during I/R remains unknown.Our study aimed t

read more

Internet of Spacecraft for Multi-Planetary Defense and Prosperity

short shifter rsx Recent years have seen unprecedentedly fast-growing prosperity in the commercial space industry.Several privately funded aerospace manufacturers, such as Space Exploration Technologies Corporation (SpaceX) and Blue Origin have transformed what we used to know about this capital-intense industry and gradually reshaped the future of

read more